megatomi.com for Dummies

Our new Clear+ tissue clearing method is the sole system that delipidates samples without having change in morphology and with minimum effect on structural integrity.

Megatome is really a vibrating microtome created to area a wide choice of samples, from organoids and biopsy samples to expanded rodent brains and intact human organs. With superior blade vibrating frequency and minimized blade deflection, Megatome enables higher-throughput tissue sectioning with uniform surface area profile, along with small tissue problems and knowledge decline.

Ask for a estimate or demo Uniformly part substantial tissues & sample arrays Megatome is the only microtome that may segment samples as substantial as intact nonhuman primate and human organs, rendering it a must have for fields which include neuropathology.

Megatome is suitable for precision: the blade vibrates at the next frequency and bigger amplitude array than other microtomes, and contains a exceptional deflection Regulate system.

SE uses a rotational electric powered subject to disperse hugely electromobile molecules (for example antibodies or surfactant micelles) during a porous sample without having damaging electrically charged buildings in the tissue. This permits 2-4 working day clearing of intact organs,

Our preformulated EasyIndex Remedy raises and homogenize the refractive index of delipidated tissue samples, rendering them totally transparent. This allows gentle penetration in to the sample and ensures the acquisition of superior-resolution, in-focus graphic knowledge.

Megatome is often a novel microtome that permits for top-precision sectioning of a wide array of tissue samples – from organoids, to arrays of animal organs, to intact human brain hemispheres – with small tissue harm and knowledge reduction.

eFLASH is a swift tissue labeling approach which allows for uniform complete-organ staining in 20 rounds of labeling.

Completely delipidate full mouse brains or comparably sized samples in just one working day megatomi.com with SmartBatch+, or in one 7 days with our passive clearing package.

Docset development necessitates at bare minimum two solutions: the title of your docset and the location with the Javadoc files to incorporate in the docset.

This may develop a docset named Sample in the current directory. Docset generation can be custom-made with optional arguments:

SHIELD avoids the variability of hydrogel embedding and the knowledge decline from PFA preservation, protecting specimens for several rounds of processing.

--displayName: Will set the name as demonstrated in Sprint. This is handy in case you make a docset with title SampleProject but Display screen name Sample Undertaking rather. This placing will default to the worth of --name if omitted.

Our novel SHIELD tissue preservation method kinds intramolecular bonds working with polyfunctional, adaptable epoxides to stabilize tissue architecture and safeguard the sample’s endogenous fluorescence, protein antigenicity and nucleic acids.